Painful night-time urination needs testing

DEAR DR. GOTT: My 63-year-old wife has been disturbed for many years by nocturnal urges to urinate that are accompanied by pain. The episodes occur three to four times a night and disturb her sleep because she has to use the toilet.

She periodically uses Vagifem (vaginal estrogen pills) but continues to wake up. She tried Detrol but it made her feel terrible. This has created a long-term problem that lessens her enjoyment of life. Any thoughts?
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