Q: I am a 43-year old woman with bipolar disease. I have been treated with it for the last 23 years. For the last 7 I have mainly experienced more severe episodes of depression and no major highs. Is this because of age or could it be due to fine tuning of my medications? I ask because I have perimenopause. Could this and menopause completely mess up my mood levels?
Mental illness runs on both sides of my family. We are all well-educated and always keep up to date on our illness.
I have been reading your column for a long time and think you are soooo intelligent and kind with your words. Thank you.
A: Thank you for the compliment. Bipolar disorder a/k/a manic depressive disorder causes serious mood swings that cover the gamut from depression to mania. Mood shifts may occur several times each day, or several times a year; there is no specific pattern. In some instances, symptoms of depression and mania can occur simultaneously.
Episodes are characterized by mania, hypomania and major depression; the subtypes include bipolar I and bipolar II. Patients who suffer from bipolar I disorder experience manic episodes and almost always experience hypomania as well as major episodes of depression. Bipolar II is defined when an individual has at least one hypomanic episode, at least one major depressive episode, and an absence of manic episodes. As you can determine, each subtype has a pattern that is different from the others. Bipolar I may cause problems with other individuals at home or in the workplace. Bipolar II is less severe, may encompass elevated mood swings and irritability, yet the individual will likely be able to function normally throughout the day. .
The manic phase of the disorder may include poor judgment, states of euphoria, aggressive behavior, rapid speech, elevated self-esteem, poor performance at work or school, and a great deal more.
On the flip side, the depressive phase may include a lack of interest in things that were once very important, anxiety, hopelessness, sadness, sleep abnormalities, difficulties concentrating, and more.
Numerous situations or conditions may modify a person’s outlook. For example, seasonal affective disorder may cause manic episodes in the spring and summer or depressed episodes in the fall or winter. There may be the loss or illness of a loved one to consider. Then there’s age. I am not implying that 43 is old by any means yet we find we might have to wear glasses, we are more concerned about diseases and disorders, we may gain or lose weight, and require medication because of medical conditions such as hypertension or hypercholesterolemia. These things may be managed with the assistance of medication, yet if we are already on one medication, there could be a crossover effect between two or more that cause symptoms we don’t completely understand.
On to the possible menopause connection. In a 2012 Psychiatric Times article, a professor at Harvard Medical School and Director of the Women’s Mental Health Division in the Department of Psychiatry at Brigham and Women’s wrote that the menstrual cycle and menopause can cause complications. Of the 2,524 women studied, 65% of women with type I and 70% of women with type II reported increased premenstrual mood symptoms. She went on to add there are a number of well-documented cases showing a clear exacerbation of mood symptoms associated with the menstrual cycle.
Speak with your therapist or prescribing physician to determine if your current medication could have any bearing on your increased depressive states, or if another tried and true medication might be more appropriate.