I take 25 milligrams of HydroDiuril and two 595-milligram doses of over-the-counter potassium gluconate. I drink several glasses of water a day plus water with my meals. Is there anything else that I can do to relieve these cramps?

DEAR READER: HydroDiuril is simply hydrochlorothiazide (HCTZ), a common medication used to treat hypertension (high blood pressure). It can cause muscle and joint pain and a reduction of potassium, which can cause cramping, but you are on supplements to avoid the common side effects. HCTZ can also cause a reduction in the amount of magnesium in your body. While studies suggest that most people may be deficient already, symptoms are not common. If your low levels are further reduced by your medication, this can lead to symptoms of deficiency, which include cramping.

Try adding a magnesium supplement to determine whether the cramping lessens. Speak to your doctor to determine how much you should take. If this doesn’t help, perhaps a change in medication is in order.

Other possible options include calcium supplements, eating pickles or drinking the juice, consuming electrolyte or sports drinks (pickles, pickle juice and sports drinks can be high in sodium, so be sure to read labels), or rubbing marjoram oil (one part marjoram to one part castor or olive oil to prevent skin irritation) over the affected areas.

To provide related information, I am sending you copies of my Health Reports “Dr. Gott’s Compelling Home Remedies” and “More Compelling Home Remedies.” Other readers who would like copies should send a self-addressed stamped No. 10 envelope and a $2 check or money order per report payable to Newsletter and mailed to Newsletter, P.O. Box 167, Wickliffe, OH 44092. Be sure to mention the title(s) or print an order form off my website at www.AskDrGottMD.com.

Twelve years ago, I had radial-nerve surgery, which was successful. I was able to use my arm and hand without any problems. However, if I engaged in an activity such as playing cards or knitting, where my hand was in the same position for any length of time, my hand cramped up and was painful. I tried the vitamin E capsule (400 IU) twice a day and very rarely have cramping anywhere in my body. If I do have a problem, I take an extra capsule immediately with the same result.

During a recent physical examination, I discussed this “remedy” with my doctor, who also reads your columns, and he said he thought you might be interested in this remedy. He said he had no idea why it works but since it does, to continue with the regimen, as this relatively small dose will not harm me. Because it is a blood thinner, I have been advised to stop taking it seven to 10 days prior to any surgery.

I am a 78-year-old Caucasian woman; however, I assume age and race have nothing to do with the results that I have had. I hope this will work as well for others.

DEAR READER: Vitamin E is a fat-soluble vitamin with antioxidant properties. It is used for the treatment and prevention of many health conditions. In fact, research remains ongoing regarding its value in treating heart conditions, Parkinson’s, diabetes, anemia, cancer and a host of other diseases and disorders. However, no conclusive studies are available for these and other conditions.

The recommended long-term daily allowance of E is between 15 and 20 IU daily; however, many experts claim it is safe when consumed in larger amounts.

Deficiency of E is rare with a proper diet that includes broccoli, spinach, kiwi, fortified cereals, whole grains, fruits, vegetables and vegetable oils, and also because it is stored in the body for extended periods of time.

There is concern regarding the safety of E in high doses because of the potential for an increased risk of bleeding, particularly in patients on anticoagulants or with a vitamin K deficiency. Excesses have been known to also cause headache, fatigue, blurred vision, diarrhea, flatulence and bloating.

If your physician thinks the 800 IU daily regimen is OK for you, stick with it, especially if it relieves your pain. Other readers should consider a modification in their diet and a discussion with their primary-care physician before taking the supplement. Medications, even those available over the counter, can interact adversely. The safest bet is to get the go-ahead first rather than backtrack after the fact.

To provide related information, I am sending you a copy of my Health Report “Vitamins & Minerals.” Other readers who would like a copy should send a self-addressed stamped No. 10 envelope and a $2 check or money order made payable to Newsletter and mailed to Newsletter, P.O. Box 167, Wickliffe, OH 44092-0167. Be sure to mention the title or print an order form off my website at www.AskDrGottMD.com.